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DNA APTAMER HAVING SPECIFIC BINDING PROPERTY TO 8-HYDROXYDEOXYGUANOSINE
DNA APTAMER HAVING SPECIFIC BINDING PROPERTY TO 8-HYDROXYDEOXYGUANOSINE
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机译:具有与8-羟基脱氧鸟嘌呤核苷特异结合的DNA适体
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摘要
PROBLEM TO BE SOLVED: To provide a DNA aptamer simply detecting an 8-OHdG (8-hydroxydeoxyguanosine) using a stable substance.;SOLUTION: The DNA aptamer is composed of a specific base sequence and has specific binding properties to the 8-OHdG. The DNA aptamer is utilized as a stress marker for evaluating the stress of a mammal. That is, a step of collecting urine of the mammal, a step of bringing the urine into contact with the fluorescent labeled DNA aptamer and a step of measuring the fluorescent label are carried out to thereby evaluate the stress of the mammal.;COPYRIGHT: (C)2007,JPO&INPIT
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