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use of glucose - 6 - phosphate - isomerase and against antibodies for diagnosis and therapeutic treatment directed by arthritisand test of treatment of arthritis active compounds

机译：葡萄糖-6-磷酸-异构酶和抗抗体在关节炎指导的诊断和治疗中的应用及对关节炎活性化合物的治疗试验

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摘要

The present invention relates to the use of antibodies against glucose-6-phosphate isomerase (GPI) and like protein for diagnosis of arthritis and the use of said protein for treatment of arthritis. It is also aimed at a process for isolating monoclonal antibodies capable of transferring arthritis and antibodies thereof, as well as a method for determining the anti-arthritic potential of a composition.

机译：本发明涉及抗6-葡萄糖磷酸异构酶（GPI）和类似蛋白质的抗体在诊断关节炎中的用途，以及所述蛋白质在治疗关节炎中的用途。本发明还针对分离能够转移关节炎的单克隆抗体的方法及其抗体，以及确定组合物的抗关节炎潜力的方法。

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公开/公告号DE60029942D1

专利类型
公开/公告日2006-09-21

原文格式PDF
申请/专利权人 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);
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申请/专利号DE2000629942T
发明设计人 BENOIST CHRISTOPHE;MATSUMOTO ISAO;KORGANOW ANNE-SOPHIE;MATHIS DIANE;MACCIONI MARIANA;JI HONG;
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申请日2000-04-21
分类号A01K67/027;A61K38/52;A61K38;A61K39/395;A61K45;A61P19/02;C07K14/46;C07K16/40;C12N5/10;C12N5/16;C12N9/90;C12N15/09;C12N15/63;C12P21/08;G01N33/53;G01N33/564;G01N33/573;
国家 DE
入库时间 2022-08-21 21:19:03

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