首页> 外国专利> MULTISTAGE DIELECTROPHORETIC SEPARATION CHIP, ITS APPLICATION TO MICROFLUIDIC SYSTEM FOR TOTAL BLOOD CELL ANALYSIS, AND ASSAYING METHOD OF THE TOTAL BLOOD CELL USING THEREOF

MULTISTAGE DIELECTROPHORETIC SEPARATION CHIP, ITS APPLICATION TO MICROFLUIDIC SYSTEM FOR TOTAL BLOOD CELL ANALYSIS, AND ASSAYING METHOD OF THE TOTAL BLOOD CELL USING THEREOF

机译:多级介电分离芯片,其在总细胞分析微流控系统中的应用,以及基于该方法的总细胞评估方法

摘要

The present invention is a multi-dielectrophoresis based microfluidic chips, it relates to the analysis of whole blood and whole blood analysis method for a microfluidic system employed, specifically, the cell or the fine particle injection unit 1, and more; Selectively deflected by an implanted cell or the fine particles in the dielectrophoretic force (dielectrophoresis force) consisting of at least one or more for the separation of various types of cells or micro particles bent portion and the microfluidic channel; And fine expansion channel (3) (microexpansion channel) portion for extending separating the deflected particles cell; Based microfluidic chips, whole blood analysis microfluidic system and the multi dielectrophoresis based for; and multi dielectrophoresis (MSDEP multistage dielectrophoresis) of that characteristic consisting of the discharge unit (4) to (7) as the number of types of the cell particle as for whole blood analysis method, according to the present invention, unlike whole blood analysis method being carried out prior, etc. front-line hospitals high cell recovery rate of the advantage that a very small amount quickly and accurately from the blood of (nl) can also conveniently be analyzed the characteristics of whole blood have. ; Multiple dielectrophoretic separation chip, trapezoidal electrode array, micro-channel expansion, separation based on biological particle analysis system
机译:本发明是基于多介电泳的微流控芯片,它涉及全血的分析和所采用的微流控系统的全血分析方法,具体地,涉及细胞或细颗粒注射单元1,等等。由植入的细胞或微粒选择性地偏转的介电泳力(dielectrophoresis force)中至少有一个或多个用于分离各种类型的细胞或微粒的弯曲部分和微流体通道;细膨胀通道(3)(微膨胀通道)部分用于延伸分离偏转的颗粒池;基于微流控芯片,全血分析微流控系统和多重介电泳为基础;根据本发明,与全血分析方法不同,本发明的全血分析方法具有由放电单元(4)至(7)组成的特征的多介电电泳(MSDEP多级介电电泳)。一线医院等在事先进行过检查后,细胞回收率高的优点是,从(nl)的血液中快速,准确地提取非常少量的血,也可以方便地分析全血的特征。 ;多重介电泳分离芯片,梯形电极阵列,微通道扩展,基于生物颗粒分析系统的分离

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