首页> 外国专利> METHOD AND VACCINE STRATEGIES FOR POTENTIATING THE IMMUNE RESPONSE TO PRIONS FOLLOWING VACCINATION, DIAGNOSTIC KITS AND PHARMACEUTICAL COMPOSITIONS FOR THE PROPHYLAXIS AND TREATMENT OF SPONGIFORM ENCEPHALOPATHIES

METHOD AND VACCINE STRATEGIES FOR POTENTIATING THE IMMUNE RESPONSE TO PRIONS FOLLOWING VACCINATION, DIAGNOSTIC KITS AND PHARMACEUTICAL COMPOSITIONS FOR THE PROPHYLAXIS AND TREATMENT OF SPONGIFORM ENCEPHALOPATHIES

机译：接种疫苗，诊断试剂盒和药物成分后预防和治疗海绵状脑病的方法和疫苗策略

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摘要

Method and novel vaccine strategies for potentiating the immune response to a prion by DNA immunisation using fusion of the prion to the LIMPII lysosome transport signal or fusion of the ubiquitin to the prion in order to overcome the immune tolerance barrier. The use of the method for developing novel preventive or therapeutic compositions and diagnostic kits is also described.

机译：通过使用病毒与LIMPII溶酶体转运信号的融合或泛素与the病毒的融合的DNA免疫来增强对to病毒的免疫应答的方法和新型疫苗策略，以克服免疫耐受屏障。还描述了该方法在开发新型预防或治疗组合物和诊断试剂盒中的用途。

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公开/公告号WO2006092457A2

专利类型
公开/公告日2006-09-08

原文格式PDF
申请/专利权人 FUNDACIÓ CENTRE DE RECERCA EN SANITAT ANIMAL;BRUN TORRES ALEJANDRO;FERNÁNDEZ BORGES NATALIA;RODRÍGUEZ GONZÁLEZ FERNANDO;LINDSAY WHITTON JAMES;
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申请/专利号WO2006ES00093
发明设计人 LINDSAY WHITTON JAMES;FERNÁNDEZ BORGES NATALIA;BRUN TORRES ALEJANDRO;RODRÍGUEZ GONZÁLEZ FERNANDO;
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申请日2006-02-28
分类号A61K39/00;C07K16/28;
国家 WO
入库时间 2022-08-21 21:29:34

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