首页> 外国专利> ANIMAL FOR DRUG EFFICACY EVALUATION, METHOD OF INDUCING ASTHMA IN ANIMAL FOR DRUG EFFICACY EVALUATION AND DRUG EFFICACY EVALUATION METHOD USING THE ANIMAL

ANIMAL FOR DRUG EFFICACY EVALUATION, METHOD OF INDUCING ASTHMA IN ANIMAL FOR DRUG EFFICACY EVALUATION AND DRUG EFFICACY EVALUATION METHOD USING THE ANIMAL

机译:用于药物功效评价的动物,在动物中引起哮喘的药物评价方法以及使用该动物进行药物功效评价的方法

摘要

It is intended to provide: an animal for drug efficacy evaluation characterized by being constructed by sensitizing a nonhuman animal by administering a sensitizer directly to its lower airway and then administering an inducer directly to the lower airway to thereby induce asthma; a method of inducing asthma in an animal for drug efficacy evaluation characterized by comprising sensitizing a nonhuman animal by administering a sensitizer directly to its lower airway and then administering an inducer directly to the lower airway; and a drug efficacy evaluation method characterized by comprising administering a drug to the animal for drug efficacy evaluation as described above and then evaluating the function/effect thereof.
机译:本发明的目的在于提供一种药效评价用动物,其特征在于,通过对非人类动物的下呼吸道直接给予敏化剂,然后对下呼吸道直接给予诱导剂,从而诱发哮喘,从而构造成哮喘。一种在动物中诱导哮喘以进行药物功效评估的方法,其特征在于包括通过将敏化剂直接施用于其下气道来使非人类动物致敏,然后将诱导剂直接施用于下气道。以及药物功效评估方法,其特征在于包括如上所述向动物施用药物以进行药物功效评估,然后评估其功能/效果。

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