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Evaluating binding affinities by force stratification and force panning

机译:通过力量分层和力量平移评估绑定亲和力

摘要

The present invention is a method for selectively removing objects from a surface utilizing a probe. The probe is scanned over the surface utilizing a greater and greater relative amount of force so that a certain number of the objects are removed from the surface. The force required to remove the objects from the surface can be calculated utilizing Hook's law and the spring constant of the probe. After removal of the objects that have a relatively weaker binding affinity with the surface, the remaining objects can be harvested, characterized, and subjected to further study.
机译:本发明是一种利用探针从表面选择性地去除物体的方法。使用越来越大的相对力在表面上扫描探针,以便从表面去除一定数量的物体。可以使用霍克定律和探头的弹簧常数来计算从表面去除物体所需的力。去除与表面的结合亲和力较弱的物体后,可以收获,表征其余物体并进行进一步研究。

著录项

  • 公开/公告号AU2002213086B2

    专利类型

  • 公开/公告日2006-09-14

    原文格式PDF

  • 申请/专利权人 BIOFORCE NANOSCIENCE INC.;

    申请/专利号AU20020213086

  • 发明设计人 ERIC HENDERSON;CURTIS MOSHER;

    申请日2001-10-10

  • 分类号G01N33/53;G01N33/543;G01Q60;C07K16/06;G01N33/566;G01Q80;

  • 国家 AU

  • 入库时间 2022-08-21 21:34:40

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