首页> 外国专利> method for identifying a member of the secfam3 family, polypeptide, purified nucleic acid molecule, vector, host cell, ligand, compound, method for diagnosing a disease in a patient, use of a polypeptide, pharmaceutical composition, vaccine composition, methods for treating a disease in a patient, to monitor the therapeutic treatment of disease in a patient, and to identify a compound that is effective in treating and / or diagnosing the disease, kit, transgenic or muted nonhuman animal, and method for screening for an effective compound to treat disease

method for identifying a member of the secfam3 family, polypeptide, purified nucleic acid molecule, vector, host cell, ligand, compound, method for diagnosing a disease in a patient, use of a polypeptide, pharmaceutical composition, vaccine composition, methods for treating a disease in a patient, to monitor the therapeutic treatment of disease in a patient, and to identify a compound that is effective in treating and / or diagnosing the disease, kit, transgenic or muted nonhuman animal, and method for screening for an effective compound to treat disease

机译:鉴定secfam3家族成员的方法,多肽,纯化的核酸分子,载体,宿主细胞,配体,化合物,用于诊断患者疾病的方法,多肽的用途,药物组合物,疫苗组合物, ,监测转基因或静音的非人类动物,试剂盒,转基因或突变的非人类动物以及用于筛选有效的化合物的方法,以监测患者的疾病的治疗性治疗,以及鉴定对疾病有效的治疗和/或诊断的化合物治疗疾病

摘要

"METHOD FOR IDENTIFYING A SECFAM3 FAMILY MEMBER, POLYPEPTID, PURIFIED NUCLEIC ACID MOLECLE, VECTOR, HOSTING CELL, DIAGNOSIS METHOD FOR A COMPACT DISEASE, TREATING A DISEASE IN A PATIENT, TO MONITOR THERAPEUTIC TREATMENT OF DISEASE IN A PATIENT, AND TO IDENTIFY A COMPOUND THAT IS EFFECTIVE IN THE TREATMENT AND / OR DIAGNOSIS OF DISEASE, KIT, HUMAN OR UNGENOUS, SILENT ANIMAL OR TRANSMITTER TREATING FOR AN EFFICIENT COMPOUND TO TREAT DISEASE ". This invention relates to a novel family of secreted proteins, called the SECFAM3 family, their family members including the new proteins INSP123, INSP124 and INSP125, identified herein as secreted proteins containing a von Willebrand type C (vWFC) factor domain and the use of these proteins and nucleic acid sequences from coding genes in the diagnosis, prevention and treatment of disease.
机译:“确定SECFAM3家族成员,多肽,纯化的核酸分子,矢量,宿主细胞,紧凑型疾病的诊断方法,治疗患者的疾病,监测治疗性疾病,对疾病的治疗和疾病治疗的方法有效治疗和/或诊断疾病,工具包,人类或不自然的,沉默的动物或发射器以治疗疾病的有效成分。”本发明涉及一种新的分泌蛋白家族,称为SECFAM3家族,它们的家族成员包括新蛋白INSP123,INSP124和INSP125,在本文中被鉴定为含有von Willebrand C型(vWFC)因子结构域的分泌蛋白,以及这些蛋白的用途。编码基因中的蛋白质和核酸序列在疾病的诊断,预防和治疗中的作用。

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