首页> 外国专利> methods of inducing the diuretic effect, inducing, maintaining or restoring the diuretic effect of a non-adenosine modifying diuretic, maintaining, restoring or improving renal function in a patient, inducing diuresis, preventing the onset of renal impairment in a patient with fluid or CHF overload, treating CHF patients and improving overall health outcomes, pharmaceutical composition and uses

methods of inducing the diuretic effect, inducing, maintaining or restoring the diuretic effect of a non-adenosine modifying diuretic, maintaining, restoring or improving renal function in a patient, inducing diuresis, preventing the onset of renal impairment in a patient with fluid or CHF overload, treating CHF patients and improving overall health outcomes, pharmaceutical composition and uses

机译：诱导非腺苷的利尿剂的利尿作用，诱导，维持或恢复利尿作用的方法，维持，恢复或改善患者肾功能，诱导利尿，预防液体或CHF患者肾功能不全的发作超负荷，治疗CHF患者并改善整体健康状况，药物成分和用途

页面导航

摘要
著录项
相似文献

摘要

"METHODS OF DIURYTIC EFFECT INDUCTION, INDUCTING, MAINTENANCE OR RESTORATION OF DIURYTIC EFFECT, NOT MODIFYING ADENOSINE, MAINTAINING, RESTORING OR IMPROVING THE RENAL DIFFICULAR RENAL FUNCTION CHF FLUID OVERLOAD, CHF PATIENT TREATMENT AND IMPROVEMENT OF GLOBAL HEALTH RESULTS, PHARMACEUTICAL COMPOSITION AND ITS USES ". A pharmaceutical composition comprising a therapeutically effective amount of KW-3902 or a salt, ester, amide, metabolite or prodrug thereof and a non-adenosine modifying diuretic is disclosed. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902 or a salt, ester, amide, metabolite or prodrug thereof in combination with a second pharmaceutical composition. able to induce a diuretic effect.

机译：“利尿作用的诱导，诱导，维持或恢复的作用方法，不改变腺嘌呤，维持，恢复或改善肾上不同的肾功能衰竭的瑞士法郎流体负荷，CHF患者的病情和治疗效果，” 。公开了包含治疗有效量的KW-3902或其盐，酯，酰胺，代谢产物或前药和非腺苷修饰的利尿剂的药物组合物。还公开了在动物中诱导利尿作用的方法，其包括与第二药物组合物组合施用治疗有效量的KW-3902或其盐，酯，酰胺，代谢物或前药的步骤。能够引起利尿作用。

著录项

公开/公告号BRPI0409699A

专利类型
公开/公告日2006-04-18

原文格式PDF
申请/专利权人 NOVACARDIA INC.;
展开▼

申请/专利号BR2004PI09699
发明设计人 KENNETH J. WIDDER;LAUREN OTSUKI;HOWARD DITTRICH;SCOTT THOMSON;ROLAND BLANTZ;
展开▼

申请日2004-04-23
分类号A61K31/522;A61K31/635;A61K31/63;A61P7/10;
国家 BR
入库时间 2022-08-21 21:40:06

相似文献

专利
外文文献