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Recombinant, biologically active human zona pellucida protein 3 (HZP3) to test male fertility
Recombinant, biologically active human zona pellucida protein 3 (HZP3) to test male fertility
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机译：重组，具有生物活性的人透明带蛋白3（HZP3），可测试男性的生育能力
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摘要
The invention relates to methods for producing recombinant human zona pellucida protein (“rhZP3”) and glycosylated peptide having biological activity of binding to human spermatozoa. A human ovarian cell line is used to produce rhZP3 having a glycosylation pattern required for full biological activity. Methods of determining useful peptides with binding activity for human sperm and their syntheses, as well as using such peptides and proteins in therapeutics and diagnostics are discussed.
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