首页>
外国专利>
Medical laboratory diagnosis of intrathecal immunoglobulin synthesis as indicator of e.g. meningitis, detects free kappa- and free lambda immunoglobulin light chains in cerebrospinal fluid
Medical laboratory diagnosis of intrathecal immunoglobulin synthesis as indicator of e.g. meningitis, detects free kappa- and free lambda immunoglobulin light chains in cerebrospinal fluid
展开▼
机译：医学实验室诊断鞘内免疫球蛋白合成可作为例如脑膜炎，检测脑脊液中的游离κ和游离λ免疫球蛋白轻链
展开▼
页面导航
摘要
著录项
相似文献
摘要
Free kappa- and/or free lambda immunoglobulin light chains are detected quantitatively in the cerebrospinal fluid of the patient. Detection follows addition of a specific antibody, and employs latex-assisted nephelometry, turbidimetry or radio-immuno assay of the cerebro-spinal fluid, for quantitative measurement. In addition, light chains are also measured in the serum. Increase of free kappa immunoglobulin light chains in the cerebro-spinal fluid, indicates an auto-immune process. Increase in the free lambda immunoglobulin light chains indicates meningitis caused by a pathogen. Conditions which may be indicated in accordance with the foregoing principles are further discussed. They include the advance of multiple sclerosis, meningitis conditions and viral or bacterial conditions e.g. associated with borrelia, or syphilis. A test strip is proposed for rapid diagnosis of meningitis initially suggested by headache symptoms. Corresponding methods of investigation are also claimed.
展开▼
