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Detecting complexes of interleukin-6 with its soluble receptor, useful e.g. in screening for agents that antagonize interaction between the complex and soluble gp130-Fc, using antibody specific for the receptor component
Detecting complexes of interleukin-6 with its soluble receptor, useful e.g. in screening for agents that antagonize interaction between the complex and soluble gp130-Fc, using antibody specific for the receptor component
Detecting the interleukin-6 (IL-6)/soluble (s) IL-6 receptor complex (A) comprising coating the surface of a reaction vessel with soluble gp130-Fc (2), saturating non-specific binding sites with albumen, binding (A) to (2), then binding an antibody (4) specific for the sIL-6 receptor, is new. An independent claim is also included for a test kit for the new method.
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