首页>
外国专利>
DEVICE AND METHOD FOR MANUFACTURING BEAD ARRAY WHICH ENABLES TO ACCURATELY SUPPLY THE BEADS WITH FIXED PROBES ON THE SURFACE TO TARGET REACTION SITE OF SOLID-PHASE SUBSTRATE, AND METHOD FOR DETECTING TARGET SUBSTANCE USING THE SAME
DEVICE AND METHOD FOR MANUFACTURING BEAD ARRAY WHICH ENABLES TO ACCURATELY SUPPLY THE BEADS WITH FIXED PROBES ON THE SURFACE TO TARGET REACTION SITE OF SOLID-PHASE SUBSTRATE, AND METHOD FOR DETECTING TARGET SUBSTANCE USING THE SAME
PURPOSE: A device and method for manufacturing bead array, and a method for detecting a target substance using the same are provided, thereby accurately supplying the beads with fixed probes consisting of nucleic acids or proteins on the surface to a target reaction site of a solid-phase substrate. CONSTITUTION: The device(10) for manufacturing bead array comprises a substrate(11); a cartridge holder(carriage) (12) which moves in forward and backward in a X-axis direction; a table(13) which moves in forward and backward in a Y-axis direction which is perpendicular to the X-axis direction; a suction unit(14) for filling the discharging solution on the cartridge holder(12); and a carriage and table operating portion(15), wherein the cartridge holder(carriage) (12) comprises a discharging head; the discharging head comprises a liquid receiving means which receives liquid containing the biological material-fixed beads; a liquid discharging means which discharges the liquid containing the biological material-fixed beads on a target reaction site on the solid-phase substrate; the liquid discharging means uses ink-jet method; the liquid receiving means separately receives two kinds of different liquid; the biological material is nucleic acid or protein; the bead size is 0.02 to 10 micrometer; the solid-phase substrate is microtiter plate; and the reaction site is formed on the wells of the substrate surface.
展开▼
