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EXTRACT OF SKIPJACK TUNA HAVING PROTECTIVE EFFECT FOR NEURONAL CELL BY INHIBITING NEURONAL CELL APOPTOSIS OCCURRED AT CEREBRAL ISCHEMIA AND COMPOSITION FOR PREVENTION AND TREATMENT OF BRAIN DISEASE COMPRISING SAME
EXTRACT OF SKIPJACK TUNA HAVING PROTECTIVE EFFECT FOR NEURONAL CELL BY INHIBITING NEURONAL CELL APOPTOSIS OCCURRED AT CEREBRAL ISCHEMIA AND COMPOSITION FOR PREVENTION AND TREATMENT OF BRAIN DISEASE COMPRISING SAME
PURPOSE: An extract of skipjack tuna having protective effect for neuronal cell and a composition for prevention and treatment of brain disease comprising the same extract are provided, which skipjack tuna extract has improved inhibitory effect for neuronal cell apoptosis occurred in cerebral ischemia and no toxicity to human body, so that it can be useful for prevention and treatment of brain disease caused by neuronal cell apoptosis. CONSTITUTION: The extract of skipjack tuna having protective effect for neuronal cell is prepared by extracting skipjack tuna with a solvent selected from water, C1-C5 alcohol, hexane, ethylacetate, chloroform and a mixture thereof. The composition for prevention and treatment of brain disease comprises the skipjack tuna extract having protective effect for neuronal cell, wherein the brain disease is caused by neuronal cell apoptosis.
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