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COMPOSITION FOR PRODUCING SUSTAINED-RELEASE POROUS MEMBRANE FOR ORAL DRUG DELIVERY SYSTEM WHICH CONTROLLABLY AND CONTINUOUSLY RELEASES DRUGS AND HAS IMPROVED STORAGE STABILITY AND THE ORAL DRUG DELIVERY SYSTEM USING THE SAME
COMPOSITION FOR PRODUCING SUSTAINED-RELEASE POROUS MEMBRANE FOR ORAL DRUG DELIVERY SYSTEM WHICH CONTROLLABLY AND CONTINUOUSLY RELEASES DRUGS AND HAS IMPROVED STORAGE STABILITY AND THE ORAL DRUG DELIVERY SYSTEM USING THE SAME
PURPOSE: A composition for producing sustained-release porous membrane for oral drug delivery system and the oral drug delivery system using the same sustained-release porous membrane are provided, which oral drug delivery system controllably and continuously releases drugs, reduces the coating cost by using a smaller amount of porous membrane, and has improved storage stability against humidity and temperature. CONSTITUTION: The composition for producing sustained-release porous membrane for oral drug delivery system comprises one or more film forming materials selected from cellulose-based compound, polymethacrylate, semipermeable polyamide and semipermeable sulfonated polystyrene; the film forming material comprises cellulose acetate and polymethylmethacrylate in a weight ratio of 2 -3:1-1.5. The oral drug delivery system comprises 0.1 to 50 parts by weight of a core containing pharmaceutical active components; and the sustained-release porous membrane containing one or more film forming materials selected from cellulose-based compound, polymethacrylate, semipermeable polyamide, semipermeable polyurethane and semipermeable sulfonated polystyrene.
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