首页> 外国专利> B LYMPHOID LINEAGE SPECIFIC PROMOTER SEQUENCES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

B LYMPHOID LINEAGE SPECIFIC PROMOTER SEQUENCES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

机译:B淋巴谱系特定启动子序列和包含相同序列的药物成分

摘要

The present invention relates to a nucleic acid sequence comprising or consisting of a S sequence, said S sequence comprising or consisting of: (1) a first sequence corresponding to a fragment of at least (10) nucleotides of the promoter sequence of the human CD19 gene, such as defined in Figure (1), the ends of which being comprised from the nucleotide at position -1400 to the nucleotide at position -1000 of the promoter sequence of the human CD19 gene, (2) a second sequence consisting of the contiguous nucleotides ranging from position - 231 to position - 1 (SEQ ID NO :1) of the promoter sequence of the human CD19 gene.
机译:本发明涉及包含或由S序列组成的核酸序列,所述S序列包含或由以下组成:(1)第一序列,其对应于人CD19的启动子序列的至少(10)个核苷酸的片段。基因,如图1所示,其末端由人CD19基因启动子序列的-1400位核苷酸至-1000位核苷酸组成,(2)由人CD19基因的启动子序列的从第231位至第-1位(SEQ ID NO:1)的连续核苷酸。

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