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A solid dosage form comprising a fibrate and a statin

机译：包含贝特类和他汀类药物的固体剂型

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摘要

The present invention relates to pharmaceutical compositions in particulate form or in solid dosage forms comprising a combination of a fibrate, notably fenofibrate, and a statin (also known as a HMG CoA reductase inhibitors), which compositions are manufactured without any need of addition of water or an aqueous medium and wherein at least 80% of the active substances (i.e. the fibrate and the statin) are present in the composition in dissolved form in order to ensure suitable bioavailability of both active ingredients upon oral administration

机译：本发明涉及颗粒形式或固体剂型的药物组合物，其包含贝特类药物，特别是非诺贝特和他汀类药物（也称为HMG CoA还原酶抑制剂）的组合，该药物组合物的制备无需添加水或水性介质，并且其中至少80％的活性物质（即贝特类药物和他汀类药物）以溶解形式存在于组合物中，以确保两种活性成分在口服时均具有适当的生物利用度

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公开/公告号AU2004279661A1

专利类型
公开/公告日2005-04-21

原文格式PDF
申请/专利权人 VELOXIS PHARMACEUTICALS A/S;
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申请/专利号AU20040279661
发明设计人 PER HOLM;TOMAS NORLING;
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申请日2004-10-01
分类号A61K9/14;A61K9/16;A61K9/20;A61K31/192;A61K31/195;A61K31/216;A61K31/22;A61K31/366;A61K31/40;A61K31/505;A61K45/06;
国家 AU
入库时间 2022-08-21 22:13:13

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