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Regulation of human alpha1A-adrenergic receptor-like G protein-coupled receptor

机译:人α1A-肾上腺素能受体样G蛋白偶联受体的调节

摘要

Reagents which regulate human alpha 1aadrenergic receptor-like GPCR and reagents which bind to human alpha 1a adrenergic receptor-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, obesity cancers, anorexia, bulimia, asthma, Parkinson's diseases, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, angina pectoris, myocardial infarction, ulcers, asthma, allergies, multiple sclerosis, benign prostatic hypertrophy, and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, several mental retardation, and dyskinesias, such as Huntington's disease and Tourett's syndrome.
机译:调节人α> 1a <肾上腺素能受体样GPCR的试剂和与人α> 1a <肾上腺素能受体样GPCR基因产物结合的试剂可在预防,改善或纠正功能障碍或疾病中发挥作用,包括但不限于,例如细菌,真菌,原生动物和病毒感染,尤其是由HIV病毒,疼痛,肥胖症癌症,厌食症,贪食症,哮喘,帕金森氏病,急性心力衰竭,低血压,高血压,尿retention留,骨质疏松症,心绞痛引起的感染,心肌梗塞,溃疡,哮喘,过敏,多发性硬化,良性前列腺肥大以及精神病和神经系统疾病,包括焦虑症,精神分裂症,躁狂抑郁症,ir妄,痴呆,若干智力低下和运动障碍,例如亨廷顿舞蹈病和图雷特氏综合症。

著录项

  • 公开/公告号DK1287137T3

    专利类型

  • 公开/公告日2005-08-08

    原文格式PDF

  • 申请/专利权人 BAYER HEALTHCARE AG;

    申请/专利号DK20010949336T

  • 发明设计人 RAMAKRISHNAN SHYAM;

    申请日2001-05-11

  • 分类号C12N15/12;A61K31/7088;A61K39/395;C07K14/705;C12N15/62;C12Q1/68;G01N33/68;

  • 国家 DK

  • 入库时间 2022-08-21 22:18:10

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