首页> 外国专利> Injectable Pharmaceutical composition comprising (a) tazobactamo, piperacillin, (b) and (c) at least one selected chelating Agent EDTA, DTPA, HEDTA, NTA, among others.And optionally a buffer and an aminoglycoside; processes for their preparation, and use to prepare Drugs useful in the treatment of Infections.

Injectable Pharmaceutical composition comprising (a) tazobactamo, piperacillin, (b) and (c) at least one selected chelating Agent EDTA, DTPA, HEDTA, NTA, among others.And optionally a buffer and an aminoglycoside; processes for their preparation, and use to prepare Drugs useful in the treatment of Infections.

机译：可注射药物组合物，其包含（a）他唑巴他莫，哌拉西林，（b）和（c）至少一种选择的螯合剂EDTA，DTPA，HEDTA，NTA，以及任选的缓冲剂和氨基糖苷;制备方法以及用于制备可用于治疗感染的药物的方法。

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Chelating Agent EDTA amino carboxylic acid or a Salt of this preference has been found to be useful for the inhibition of Formation of particulates in parenteral combinationsIn tazobactamo piperacillin. The composition may also contain a buffer, preferably Citrate, and optionally an aminoglycoside.The Product can be in the form of a composition that can be Frozen thawed for use.The Product can also take the form of a Powder criodisecado which can be reconstituted by the addition of an aqueous vehicle to form a solution.

机译：已发现这种偏好的螯合剂EDTA氨基羧酸或盐可用于抑制他唑巴他莫哌拉西林肠胃外组合物中微粒的形成。该组合物还可以包含缓冲剂，优选柠檬酸盐，和任选地氨基糖苷。该产品可以是可以冷冻融化使用的组合物的形式。该产品还可以是可以通过以下方法重构的粉状criodisecado的形式。添加水性载体以形成溶液。

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公开/公告号CL2004000782A1

专利类型
公开/公告日2005-03-04

原文格式PDF
申请/专利权人 WYETH HOLDINGS CORPORATION;
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申请/专利号CL20040000782
发明设计人 COHEN JONATHAN MARC;SHAH SYED MUZAFAR;OFSLAGER CHRISTIAN LUTHER;FAWZI MAHDI BAKIR;
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申请日2004-04-12
分类号A61K31/43;A61K31/431;A61K31/496;A61K47/12;A61K47/18;A61P31/00;A61P31/04;
国家 CL
入库时间 2022-08-21 22:18:21

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