首页> 外国专利> The process of obtaining eristostatina / alkaline phosphatase chimeric; construction of eristostatina / alkaline phosphatase and its chimeric product expressed in periplasma; use of proteu00ecna fusion eristotatina/ alkaline phosphatase and diagnostic kit

The process of obtaining eristostatina / alkaline phosphatase chimeric; construction of eristostatina / alkaline phosphatase and its chimeric product expressed in periplasma; use of proteu00ecna fusion eristotatina/ alkaline phosphatase and diagnostic kit

机译：获得Eristostatina /碱性磷酸酶嵌合体的过程; Eristostatina碱性磷酸酶的构建及其在周质中表达的嵌合产物使用Proteu u00ecna融合蛋白/碱性磷酸酶和诊断试剂盒

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"The process of obtaining eristostatina / alkaline phosphatase chimeric; construction of eristostatina / alkaline phosphatase and its chimeric product expressed in periplasma; use of the fusion protein eristostatiIn / alkaline phosphatase and diagnostic kit.The present invention patent refers to a process for obtaining eristostatina / alkaline phosphatase chimeric construction of the chimera eristostatina / alkaline phosphatase (ER / APV)The expression and production of periplasma bacterial, and its direct use as molecular marker in which the integrin IIB 244 ~ ~ 225 ~ 3 ~ is detected in a single step and kit for diagnosis.By means of the invention is a product eristostatina / alkaline phosphatase.Could be used directly as a tool for prognosis / diagnosis in diseases where the integrin 244 ~ B ~ 225 ~ 3 ~ is involved.The versatility of the marker allows the detection by dot blot and ELISA, and histochemical techniques.

机译：“获得埃氏菌属/碱性磷酸酶嵌合体的方法;构建埃氏菌属/碱性磷酸酶及其嵌合体在周质中表达;融合蛋白eristostatiIn /碱性磷酸酶和诊断试剂盒的用途。用于获得嵌合体的埃氏菌属/碱性磷酸酶的嵌合结构埃氏菌属/碱性磷酸酶（ER / APV）的表达和产生周质细菌，并将其直接用作整合素IIB <244>〜〜<225的分子标记在一步和试剂盒中可检测到≥3〜。通过本发明的方法，该产品是埃氏抑菌酶/碱性磷酸酶产品。可直接用作整联蛋白<244>〜的疾病的预后/诊断工具。涉及到B〜<225>〜3〜。标记的多功能性使得可以通过斑点印迹和ELISA以及组织化学技术进行检测。

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公开/公告号BR0300212A

专利类型
公开/公告日2005-02-22

原文格式PDF
申请/专利权人 UNIAO QUIMICA FARMACEUTICA NACIONAL S/A;FUNDACAO DE AMPARO A PESQUISA DA ESTADO DE SAO PAULO - FAPESP;ANA MARIA MOURA DA SILVA;
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申请/专利号BR20030300212
发明设计人 ANA MARIA MOURA DA SILVA;DIEGO ALBERTO BUTERA WADSWORTH;
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申请日2003-01-31
分类号C12Q1/56;C07K19/00;
国家 BR
入库时间 2022-08-21 22:18:44

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