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Use of substance P antagonists for the treatment of chronic fatigue syndrome and/or fibromyalgia and use of NK-1 receptor antagonists for the treatment of chronic fatigue syndrome
Use of substance P antagonists for the treatment of chronic fatigue syndrome and/or fibromyalgia and use of NK-1 receptor antagonists for the treatment of chronic fatigue syndrome
The invention relates to the use of specific substance P antagonists, in particular, 1-acylpiperidine substance P antagonists, especially N-benzoyl-2-benzyl-4-(azanapthoyl-amino)-piperidines, which are unsubsituted or mono- or poly-substituted by substituents selected from the group consisting of lower alkyl, lower alkoyl, halogen, nitro and trifluoromethyl; and pharmaceutically acceptable salts thereof for treatment of chronic fatigue syndrome (CFS) or for the treatment of fibromyalgia or fibromyalgia associated functional symptoms.
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