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Polysaccharide extract from Lycium barbarum as neuroprotective agent against beta-amyloid peptide neurotoxicity

机译：枸杞多糖提取物作为抗β淀粉样肽神经毒性的神经保护剂

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摘要

Extracts of Lycium barbarum serve as a neuroprotective agent against β-amyloid peptide neurotoxicity which thus permits their use for the treatment of Alzheimer's disease (AD) and for the prevention of neuronal loss in aging against the accumulation of β-amyloid peptide in the brain. Stress kinases (c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase) are used as a technological platform for screening neuroprotective drugs.

机译：枸杞子的提取物可作为抗β-淀粉样肽神经毒性的神经保护剂，因此可用于治疗阿尔茨海默氏病（AD）并预防衰老过程中针对β积累的神经元丢失。 -淀粉样蛋白肽在大脑中。应激激酶（c-Jun N端激酶和双链RNA依赖性蛋白激酶）被用作筛选神经保护药物的技术平台。 展开▼

著录项

公开/公告号US2005170028A1

专利类型

公开/公告日2005-08-04

原文格式PDF

申请/专利权人 RAYMOND CHUEN-CHUNG CHANG;WAI-HUNG YUEN;KWOK-FAI SO;S.Y. ZEE;
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申请/专利号US20050048868

发明设计人 RAYMOND CHUEN-CHUNG CHANG;S.Y. ZEE;WAI-HUNG YUEN;KWOK-FAI SO;
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申请日2005-02-03

分类号A61K31/715;C08B37/00;A61K35/78;

国家 US

入库时间 2022-08-21 22:22:16

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3. POLYSACCHARIDE EXTRACT FROM LYCIUM BARBARUM AS NEUROPROTECTIVE AGENT AGAINST BETA-AMYLOID PEPTIDE NEUROTOXICITY [P] . 世界知识产权组织专利： WO2006114019A8 . 2007-01-11

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4. POLYSACCHARIDE EXTRACT FROM LYCIUM BARBARUM AS NEUROPROTECTIVE AGENT AGAINST BETA-AMYLOID PEPTIDE NEUROTOXICITY [P] . 世界知识产权组织专利： WO2006114019A1 . 2006-11-02

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5. Lycium barbarum polysaccharide extract as a neuroprotective agent against β-amyloid peptide neurotoxicity [P] . 德国专利： DE112005001269T5 . 2008-05-29

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