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Cells in which the activity of proteins involved in the transport of GDP- fucose is decreased or deleted

机译:细胞中GDP-岩藻糖运输中涉及的蛋白质活性降低或缺失的细胞

摘要

Cells in which the activity of proteins involved in transport to the Golgi of an intracellular sugar nucleotide GDP- fucose has been deleted or lower than the parent cell, method of manufacturing the antibody composition using the cell, intracellular sugar nucleotide GDP- fucose way in which the activity of proteins involved in transport to the Golgi of so deleted or reduced, to produce the antibody composition or its progeny plants, or transgenic non-human animal genome has been altered, from a plant or animal , and medicament containing the antibody composition.
机译:细胞中糖蛋白GDP-岩藻糖转运至高尔基体的蛋白质的活性已被删除或低于亲代细胞的细胞,使用该细胞的抗体组合物的制造方法,细胞内糖核苷酸GDP-岩藻糖的制备方法因此,从植物或动物以及含有该抗体组合物的药物中改变了这样缺失或减少的,转运至高尔基体的蛋白质的活性以产生抗体组合物或其后代植物,或转基因非人动物基因组。

著录项

  • 公开/公告号JPWO2003085102A1

    专利类型

  • 公开/公告日2005-08-11

    原文格式PDF

  • 申请/专利权人 協和醗酵工業株式会社;

    申请/专利号JP20030582281

  • 发明设计人 神田 豊;佐藤 光男;森 勝弘;

    申请日2003-04-09

  • 分类号C12N15/09;A01H5/00;A01K67/027;A61K39/395;A61P9/00;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P37/08;C07K14/47;C12N5/10;C12P21/02;C12P21/08;

  • 国家 JP

  • 入库时间 2022-08-21 22:27:07

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