首页> 外国专利> USE OF DERIVATIVES OF 2-HYDROXY-4-TRIFLUORMETHYLBENEOIC ACID AS AN INHIBITOR FOR ACTIVATING THE NUCLEAR TRANSCRIPTION FACTOR NF- (K) B

USE OF DERIVATIVES OF 2-HYDROXY-4-TRIFLUORMETHYLBENEOIC ACID AS AN INHIBITOR FOR ACTIVATING THE NUCLEAR TRANSCRIPTION FACTOR NF- (K) B

机译：使用2-羟基-4-三氟甲基苯甲酸衍生物作为抑制剂来激活核转录因子NF-（K）B

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摘要

The invention relates to the use of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF- kappa B. The invention also relates to the utilization of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives for the preparation of medicaments to treat or prevent of pathologies associated to the activation of NF- kappa B and/or the expression of genes which are dependent on or regulated by, at least partially, NF- kappa B in mammals, including humans. IMAGE

机译：本发明涉及2-羟基-4-三氟甲基苯甲酸衍生物作为核转录因子NF-κB活化的抑制剂的用途。本发明还涉及2-羟基-4-三氟甲基苯甲酸衍生物用于核转录因子NF-κB活化的用途。制备用于治疗或预防与包括人在内的哺乳动物中NF-κB活化和/或依赖或至少部分受NF-κB调节的基因相关的病理的药物。 <图像>

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公开/公告号DE69910019T2

专利类型
公开/公告日2004-05-06

原文格式PDF
申请/专利权人 J. URIACH & CIA. S.A. BARCELONA ES;
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申请/专利号DE19996010019T
发明设计人 MERLOS ROCA MANUEL E-08021 BARCELONA ES;FERNANDEZ DE ARRIBA ALBERTO E-08025 BARCELONA ES;CAVALCANTI DE MARIA FERNANDO E-08026 BARCELONA ES;MIRALLES ACOSTA AGUSTI E-08400 GRANOLLERS ES;SANCHEZ CRESPO MARIANO E-47008 VALLADOLID ES;GARCIA RAFANELL JULIAN E-08017 BARCELONA ES;FORN DALMAU JAVIER E-08034 BARCELONA ES;
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申请日1999-05-26
分类号A61K31/60;H01Q1/24;D06P5/13;C12N15/63;A61P31/00;A61P35/00;A61P19/02;A61P17/06;A61K38/00;A61P29/00;A61P37/06;
国家 DE
入库时间 2022-08-21 22:40:10

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