首页> 外国专利> NOVEL ACID POLYSACCHARIDE HAVING ANTI-CANCER IMMUNOREGULATORY EFFECT WHICH IS PURIFIED FROM RED GINSENG AND COMPOSITION FOR ANTI-CANCER IMMUNOREGUATION COMPRISING SAME

NOVEL ACID POLYSACCHARIDE HAVING ANTI-CANCER IMMUNOREGULATORY EFFECT WHICH IS PURIFIED FROM RED GINSENG AND COMPOSITION FOR ANTI-CANCER IMMUNOREGUATION COMPRISING SAME

机译:具有红细胞生成的抗癌免疫调节作用的新型氨基酸多糖及其组成相同的抗癌免疫调节剂的组成

摘要

PURPOSE: A new red ginseng acid polysaccharide(RGAP) having an immunoregulatory effect on mammals separated from Ginseng Radix rubra is provided. Because the RGAP exhibits an anticancer and immunoregulatory effect, life extending effect and antitumor effect on a mouse transplanted with cancer cells, a pharmaceutical composition containing the same can be effectively used as an anticancer and immunoregulator. CONSTITUTION: The RGAP has a sugar composition comprising 41.6 to 60.0% by weight of glucuronic acid, 2.5 to 7.5% by weight of galacturonic acid, 18.8 to 33.4% by weight of glucose and 1.1 to 2.1% by weight of arabinose and a molecular weight of 12,000 to 450,000. Ginseng Radix rubra is extracted in lower alcohol, and the residue thereof is heated in water to produce a hot water extract, which is dialyzed and centrifuged in lower alcohol to produce the RGAP.
机译:目的:提供一种新的红参酸多糖(RGAP),对人参板蓝根分离的哺乳动物具有免疫调节作用。因为RGAP对移植有癌细胞的小鼠表现出抗癌和免疫调节作用,寿命延长作用和抗肿瘤作用,所以包含其的药物组合物可以有效地用作抗癌和免疫调节剂。组成:RGAP的糖组合物包含41.6至60.0重量%的葡萄糖醛酸,2.5至7.5重量%的半乳糖醛酸,18.8至33.4重量%的葡萄糖和1.1至2.1重量%的阿拉伯糖和分子量12,000至450,000。在低级醇中提取人参红花,其残余物在水中加热以产生热水提取物,将其在低级醇中透析并离心以生成RGAP。

著录项

  • 公开/公告号KR100450061B1

    专利类型

  • 公开/公告日2004-09-24

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20010033115

  • 申请日2001-06-13

  • 分类号A61K31/70;

  • 国家 KR

  • 入库时间 2022-08-21 22:46:36

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