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ANTICONVULSANT MATERIAL SEPARATED FROM GASTRODIAE RHIZOMA HAVING THERAPEUTIC EFFECT ON SEIZURE AND CONVULSION
ANTICONVULSANT MATERIAL SEPARATED FROM GASTRODIAE RHIZOMA HAVING THERAPEUTIC EFFECT ON SEIZURE AND CONVULSION
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机译：从天麻根瘤菌中分离出的抗惊厥物质，具有对麻醉和惊厥的治疗作用
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摘要
PURPOSE: An anticonvulsant material separated from a Gastrodiae Rhizoma extract having a therapeutic effect on seizure and convulsion is provided. The material is useful in increasing GABA (γ-aminobutyrate) levels in pathological states by reducing immunologic reactivity of GABA-T, SSADH and SSAR. CONSTITUTION: The anticonvulsant material having a therapeutic effect on seizure and convulsion is separated from a Gastrodiae Rhizoma extract. The material is gastrodin and used in increasing GABA levels. The Gastrodiae Rhizoma extract obtained by extracting with ethyl acetate, n-butanol and water and fractioning with n-butanol. A pharmaceutical composition containing the Gastrodiae Rhizoma extract can be used as a therapeutic agent for the treatment of convulsion and its daily dose is about 0.001μg to 100mg per kg body weight per day.
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