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Pharmaceutical preparation for the improved treatment of blood-clotting disorders

机译:用于改善凝血功能障碍的药物制剂

摘要

The present invention relates to a pharmaceutical preparation for the improved treatment of blood-clotting disorders containing one or several factor VIII derived peptides which increases the plasma half life of factor VIII. Further, such peptides, their DNA-sequences, their recombinant expression as albumin fusion proteins and vectors containing such DNA-sequences as well as host cells for such recombinant expression vectors and the use of such DNA-sequences in a transfer vector for gene therapy are disclosed.
机译:本发明涉及用于改善治疗凝血障碍的药物制剂,其含有一种或几种衍生自因子VIII的肽,该肽增加了因子VIII的血浆半衰期。此外,这些肽,它们的DNA序列,它们作为白蛋白融合蛋白的重组表达和包含这种DNA序列的载体以及用于这种重组表达载体的宿主细胞以及这种DNA序列在转移载体中用于基因治疗的用途是披露。

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