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METHOD FOR INDUCING AN IMMUNE RESPONSE TO POLYSACCHARIDE BACTERIAL ANTIGENS AND TO PROTEIN STRUCTURES OF VIRUS CAPSIDS
METHOD FOR INDUCING AN IMMUNE RESPONSE TO POLYSACCHARIDE BACTERIAL ANTIGENS AND TO PROTEIN STRUCTURES OF VIRUS CAPSIDS
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机译:诱导对多糖细菌抗原和病毒荚膜蛋白结构的免疫反应的方法
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摘要
The invention concerns an immunogenic composition, in a pharmaceutically acceptable carrier, for specifically stimulating a sub-population of B M+D+CD27+ cells so as to provide T-independent anti-bacterial response in said cells. The invention also concerns the use for producing T-independent anti-bacterial immune responses in subjects infected or susceptible of being infected by polysaccharide bacteria (streptococcus, meningococcus, pneumococcus, hemophilus influenza) or by protein capsid viruses (poliovirus, encephalomyocarditis virus, influenza virus).
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机译:本发明涉及在药学上可接受的载体中的免疫原性组合物,其用于特异性刺激BM + D + CD27 +细胞的亚群,从而在所述细胞中提供非T依赖性的抗菌反应。本发明还涉及在被多糖细菌(链球菌,脑膜炎球菌,肺炎球菌,血友病流感)或衣壳蛋白病毒(脊髓灰质炎病毒,脑心肌炎病毒,流感病毒)感染或易感染的受试者中产生非T依赖性抗菌免疫应答的用途。 )。
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