首页> 外国专利> USE OF COMPOSITIONS DEPLETED OF DENDRITIC CELLS FOR IMPROVING ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION

USE OF COMPOSITIONS DEPLETED OF DENDRITIC CELLS FOR IMPROVING ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION

机译:使用枯竭树突状细胞的组合物改善同种异体造血细胞移植

摘要

Methods of reducing or preventing graft versus host disease in an allogeneic hematopoietic system reconstituting cells transplant recipient comprising administering to the recipient allogeneic hematopoietic system reconstituting cells in which the number of dendritic cells has been effectively reduced, thereby reducing or preventing graft versus host disease, are provided. Also provided are methods of increasing the chance of survival for an allogeneic hematopoietic system reconstituting cells transplant recipient comprising administering to the recipient allogeneic hematopoietic system reconstituting cells in which the number of dendritic cells has been effectively reduced, thereby improving the chance for survival of the recipient. Columns for preparing hematopoietic system reconstituting cells prior to their transplantation are disclosed that provide for the selection of CD34+ cells and the removal of dendritic cell progenitors.
机译:减少或预防同种异体造血系统重构细胞移植受者中的移植物抗宿主疾病的方法,包括向所述受体施用已有效减少树突细胞数量从而减少或预防移植物抗宿主病的同种异体造血系统重构细胞。提供。还提供了增加异基因造血系统重构细胞移植受者的存活机会的方法,该方法包括对所述受体施用已有效减少了树突细胞数量的异基因造血系统重构细胞,从而提高了受体存活的机会。 。公开了用于在移植之前制备重建造血系统的细胞的柱,其提供了CD34 +细胞的选择和树突状细胞祖细胞的去除。

著录项

  • 公开/公告号EP1123384B1

    专利类型

  • 公开/公告日2004-04-07

    原文格式PDF

  • 申请/专利权人 EMORY UNIVERSITY;

    申请/专利号EP19990961649

  • 发明设计人 WALLER EDMUND K.;

    申请日1999-11-10

  • 分类号C12N5/00;

  • 国家 EP

  • 入库时间 2022-08-21 22:56:34

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号