首页> 外国专利> METHOD OF TREATING AND/OR PREVENTING ACUTE LEUKEMIA USING MEDICINAL COMPOSITION FOR THERAPEUTIC USE CONTAINING VLA4 ANTAGONIST, AND METHOD OF DIAGNOSING PROGNOSIS OF ACUTE LEUKEMIA USING VLA4 AS INDICATION

METHOD OF TREATING AND/OR PREVENTING ACUTE LEUKEMIA USING MEDICINAL COMPOSITION FOR THERAPEUTIC USE CONTAINING VLA4 ANTAGONIST, AND METHOD OF DIAGNOSING PROGNOSIS OF ACUTE LEUKEMIA USING VLA4 AS INDICATION

机译：含VLA4拮抗剂治疗和/或预防急性白血病的方法，以及用于治疗急性白血病的方法

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摘要

Medicinal compositions for treating acute leukemia whereby the interaction between fibronectin and VLA4 is inhibited by using a VLA4 antagonist to thereby regulate the acquisition of cell adhesion-depending anticancer agent-tolerance by leukemic cells; a method of treating and/or preventing acute leukemia using these compositions; and a method of diagnosing acute leukemia based on the VLA4 expression ratio in acute leukemic cells.

机译：用于治疗急性白血病的药物组合物，其中通过使用VLA4拮抗剂抑制纤连蛋白与VLA4之间的相互作用，从而调节白血病细胞对依赖细胞粘附的抗癌剂耐受性的获得;使用这些组合物治疗和/或预防急性白血病的方法;一种基于急性白血病细胞中VLA4表达比的急性白血病诊断方法。

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公开/公告号WO03097097A1

专利类型
公开/公告日2003-11-27

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申请/专利权人 NIITSU YOSHIRO;MATSUNAGA TAKUYA;MIYAKE KENSUKE;SAKAMAKI SUMIO;AKIYAMA TAKEHIDE;FUJIMI AKIHITO;TANAKA IKUTA;TAKEMOTO NAOFUMI;
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申请/专利号WO2002JP04704
发明设计人 NIITSU YOSHIRO;MATSUNAGA TAKUYA;MIYAKE KENSUKE;SAKAMAKI SUMIO;AKIYAMA TAKEHIDE;FUJIMI AKIHITO;TANAKA IKUTA;TAKEMOTO NAOFUMI;
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申请日2002-05-15
分类号A61K45/00;A61K39/395;A61P35/02;
国家 WO
入库时间 2022-08-21 22:59:58

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