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Short interfering rnas having a hairpin structure containing a non-nucleotide loop
Short interfering rnas having a hairpin structure containing a non-nucleotide loop
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机译:具有包含非核苷酸环的发夹结构的短干扰RNA
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摘要
This invention provides a short interfering hairpin RNA having the structure X1-L-X2, wherein X1 and X2 are nucleotide sequences having sufficient complementarity to one another to form a double-stranded stem hybrid and L is a loop region comprising a non-nucleotide linker molecule, wherein at least a portion of one of the nucleotide sequences located within the double-stranded stem is complementary to a sequence of said target RNA.
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