首页> 外国专利> DETERMINATION OF THE PROPENSITY OF AN ORGAN OR A TISSUE TO CANCER BY DETERMINATION OF ITS PRINT PATTERN.

DETERMINATION OF THE PROPENSITY OF AN ORGAN OR A TISSUE TO CANCER BY DETERMINATION OF ITS PRINT PATTERN.

机译:通过确定其印刷图案来确定器官或组织对癌症的倾向。

摘要

Compositions and procedures are provided for the diagnosis and treatment of diseases that are associated with the imprint. Such compositions and procedures are useful for restoring a normal imprint model. The compositions comprise pharmacological agents that are involved in the imprint and that can be used in preventive and therapeutic procedures to restore a normal imprint model. Such agents can restore a normal pattern of imprinting in cells. Other methods of the invention include means for identifying pharmacological compounds that exert their effect by restoring the normal imprint on chromosomes and genes with abnormal imprinting. In addition, the invention could also be used to identify new compounds that exert their effect by restoring the normal imprint in diseased tissues that have an underlying abnormal imprint.
机译:提供用于诊断和治疗与烙印有关的疾病的组合物和程序。这样的组合物和程序可用于恢复正常的印记模型。该组合物包含涉及压印的药理剂,其可以用于预防和治疗程序以恢复正常的压印模型。这样的试剂可以恢复细胞中印迹的正常模式。本发明的其他方法包括鉴定通过恢复染色体上正常印记和具有异常印记的基因而发挥作用的药理化合物的手段。另外,本发明还可用于鉴定通过恢复具有潜在异常印记的患病组织中的正常印记而发挥作用的新化合物。

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