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首页> 外国专利> A preparation of standard blood cells suspended in normal saline and a method of producing a preparation of standard blood cells suspended in normal saline.

A preparation of standard blood cells suspended in normal saline and a method of producing a preparation of standard blood cells suspended in normal saline.

机译：悬浮在生理盐水中的标准血细胞制剂和制备悬浮在生理盐水中的标准血细胞制剂的方法。

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1. A preparation of standard blood cells suspended in normal saline, where the blood cells are erythrocytes with appropriate blood-group antigens. Characterized by that the suspension of blood cells with blood concentration of ca. 4.5 or ca. 10 percent by weight, depending on applied testing method, which, following standardisation, were enriched with 2-3 percent by volume of aloe juice of Aloe vera type, contains an addition in the form of at least 0.03-0.06 percent by weight of purine base, preferably adenine as a stabilizer of the buffered normal saline, supplemented with an addition of an antibiotic from the group of amphenicols, preferably detreomycin in the amount of, preferably, 0.024 percent by weight. 2. A method of producing a preparation of standard blood cells suspended in normal saline, where the blood cells are erythrocytes with appropriate blood-group antigens, by rinsing the blood cells sediment and putting them into a liquid conservant. Characterized in that: in a sterile process, the sediment of blood cells of appropriate blood group in the amount needed to obtain a suspension with blood concentration of ca. 4.5 or ca. 10 percent by weight, depending on applied testing method, rinsed at least twice with buffered normal saline of multiple volume is poured over with a conserving liquid in the form of a buffered normal saline, stabilised and additionally sterilised. An addition is added to the saline in the form of 0.03-0.06 percent by weight of purine base, preferably adenine, and before sterilisation, there are also added preferably 0.25 g/l of an antibiotic from the group of amphenicols, preferably detreomycin; and further aloe juice of Aloe Vera type in the amount required to obtain the concentration of 2-3 percent by volume is added to the blood cells suspension following the standardization.
机译：1.悬浮在生理盐水中的标准血细胞的制剂，其中血细胞是具有适当血型抗原的红细胞。其特点是血细胞悬浮液的血药浓度约为ca。 4.5或ca.取决于应用的测试方法，按重量计10％，在标准化后富含2-3％（体积）芦荟类型的芦荟汁，其中所含的嘌呤含量至少为0.03-0.06％（重量）碱，优选腺嘌呤作为缓冲生理盐水的稳定剂，并添加了氨酚类药物，优选地曲霉素的抗生素，其量优选为0.024重量％。 2.一种通过漂洗血细胞沉淀物并将其放入液体防腐剂中来制备悬浮在生理盐水中的标准血细胞制剂的方法，其中血细胞是具有适当血型抗原的红细胞。其特征在于：在无菌过程中，适当血型的血细胞沉淀物的量为获得血药浓度为ca的悬浮液所需的量。 4.5或ca.根据所应用的测试方法，按重量计10％的溶液用多种体积的缓冲生理盐水冲洗至少两次，然后倒入缓冲生理盐水形式的保存液中，进行稳定化处理并进一步灭菌。以0.03-0.06重量％的嘌呤碱，优选腺嘌呤的形式添加到盐水中，并且在灭菌之前，还优选添加0.25g / l的氨苄青霉素类的抗生素，优选地是曲霉素。在标准化后，将获得芦荟汁类型的芦荟汁以达到2-3体积％的浓度添加到血细胞悬浮液中。

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