首页> 外国专利> Protein, purified protein fragment, purified molecule, nucleic acid, vector, recombinant cell, methods of producing a recombinant protein, treatment of an individual with a central nervous system neoplastic disease and damage to the central nervous system, inducing regeneration or sprouting of neurons in an individual, promoting structural plasticity of an individual's central nervous system, and recombinant non-human animal, method of obtaining polyclonal antibodies to a protein, isolated antiserum sample, and method of immunization of a non-human animal

Protein, purified protein fragment, purified molecule, nucleic acid, vector, recombinant cell, methods of producing a recombinant protein, treatment of an individual with a central nervous system neoplastic disease and damage to the central nervous system, inducing regeneration or sprouting of neurons in an individual, promoting structural plasticity of an individual's central nervous system, and recombinant non-human animal, method of obtaining polyclonal antibodies to a protein, isolated antiserum sample, and method of immunization of a non-human animal

机译：蛋白质，纯化的蛋白质片段，纯化的分子，核酸，载体，重组细胞，产生重组蛋白质的方法，患有中枢神经系统赘生性疾病和中枢神经系统损伤的个体的治疗，诱导神经元的再生或发芽促进中枢神经系统结构可塑性的个体和重组非人类动物，获得蛋白质多克隆抗体的方法，分离的抗血清样品以及对非人类动物进行免疫的方法

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摘要

"PROTEIN PURIFIED FRAGMENT OF A PURIFIED PROTEIN, NUCLEIC ACID, VECTOR, RECOMBINING CELL, METHODS OF PRODUCING A RECOMBINATING PROTEIN WITH A NUCLEAR DISEASE WITH A NUCLEAR CENTRAL DISEASE BURTATION OF NEURANS IN AN INDIVIDUAL, PROMOTION OF STRUCTURAL PLASTICITY OF THE CENTRAL NERVOUS SYSTEM OF AN INDIVIDUAL, RECOMBINANT NON-HUMAN ANIMAL, METHOD OF OBTAINING ANY-SUN PROTEIN MATTER ANTIBODIES Non-Human Animal. " The present invention relates to the gene, Nogo, its encoded protein products, as well as derivatives and analogs thereof. Production of Nogo antibodies, derivatives and proteins is also provided. The invention further relates to therapeutic compositions and diagnostic and therapeutic processes.

机译：“蛋白纯化的片段，蛋白的纯化片段，核酸，载体，重组细胞，生产带有核病的重组蛋白的方法，以及在单个个体中通过单个持续时间的原发性核的核中枢来促进神经元的发展。个体，重组的非人类动物，获取任何动物蛋白物质抗体的方法非人类动物“本发明涉及基因，Nogo，其编码的蛋白质产物，及其衍生物和类似物。还提供了Nogo抗体，衍生物和蛋白质的生产。本发明进一步涉及治疗组合物以及诊断和治疗方法。

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公开/公告号BR9915137A

专利类型
公开/公告日2004-06-08

原文格式PDF
申请/专利权人 MARTIN E. SCHWAB;MAIO S. CHEN;
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申请/专利号BR19999915137
发明设计人 MARTIN E. SCHWAB;MAIO S. CHEN;
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申请日1999-11-05
分类号C07K7/00;C07K14/00;C07K14/435;C07K14/47;C07K14/475;
国家 BR
入库时间 2022-08-21 23:11:49

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