首页> 外国专利> Use of chloroquine, hydroxychloroquine and 4-aminoquinoline derivatives to obtain a drug for antiretroviral therapy, which is effective against sensitive hiv virus strains, hiv virus strains resistant to nucleoside analogous non-reverse transcriptase inhibitors nucleoside analogues and against hiv virus strains resistant to protease inhibitors

Use of chloroquine, hydroxychloroquine and 4-aminoquinoline derivatives to obtain a drug for antiretroviral therapy, which is effective against sensitive hiv virus strains, hiv virus strains resistant to nucleoside analogous non-reverse transcriptase inhibitors nucleoside analogues and against hiv virus strains resistant to protease inhibitors

机译：氯喹，羟基氯喹和4-氨基喹啉衍生物用于获得抗逆转录病毒疗法的药物的作用，该药物对敏感的HIV病毒株，对核苷类似的非逆转录酶抑制剂有抵抗力的HIV病毒株对核苷类似物和对蛋白酶抑制剂有抵抗力的HIV病毒株均有效

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"USE OF CHLOROCHIN, HYDROXYCHLOROKIN AND 4-AMINOKINOLINE DERIVATIVES FOR OBTAINING AN DRUG FOR ANTI-RETROVIRAL THERAPY, AGAINST HIV-RESISTANT INIBRESIVE INFRESIVE VIRUS CIRMS AND NOT ANALOGUE OF NUCLEOSIDES AND AGAINST HIV VIRUS CEPAS RESISTANT TO PROTEASE INHIBITORS ". It refers to the use of at least one 4-aminoquinoline derivative to obtain a drug for antiretroviral therapy, in particular for the treatment of infectious diseases caused by the HIV virus, whose retroviral strains are sensitive and / or resistant to therapies. known. Said 4-aminoquinoline derivatives are chloroquine and / or hydroxychloroquine and said drug may be administered orally once or several times a day.

机译：“使用氯霉素，羟氯尿蛋白和4-氨基代茶碱衍生物进行抗病毒治疗药物，可抵抗艾滋病毒的侵袭性病毒感染，而不是模拟核苷并抵抗艾滋病毒的诱因”。它涉及至少一种4-氨基喹啉衍生物用于获得抗逆转录病毒疗法的药物的用途，特别是用于治疗由HIV病毒引起的感染性疾病的药物，其逆转录病毒株对治疗敏感和/或耐药。众所周知。所述4-氨基喹啉衍生物是氯喹和/或羟基氯喹，并且所述药物可以每天口服一次或几次。

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公开/公告号BR0304890A

专利类型
公开/公告日2004-04-13

原文格式PDF
申请/专利权人 VALPHARMA S.A.;
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申请/专利号BR20030304890
发明设计人 ROBERTO VALDUCCI;TIZIANO ALIGHIERI;SEROZH AVANESSIAN;
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申请日2003-06-26
分类号A61K31/4706;A61P31/18;
国家 BR
入库时间 2022-08-21 23:11:51

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