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首页> 外国专利> Lu00ecquido crystalline phases (lamellar and cubic) as a release system for topical use of compounds fotossensu00ecveis photosensitizers of families of ftalocianinas,Porphyrins and clorinas used in photodynamic therapy (PDT) and fotodiagnu00f3sticos (FD)

Lu00ecquido crystalline phases (lamellar and cubic) as a release system for topical use of compounds fotossensu00ecveis photosensitizers of families of ftalocianinas,Porphyrins and clorinas used in photodynamic therapy (PDT) and fotodiagnu00f3sticos (FD)

机译：Lecquido晶相（片晶和立方晶）作为局部释放化合物，用于光动力疗法（PDT）和fotodiagn u00f3sticos（FD）中的泛函胺属，卟啉和clorinas家族的fotossens u00ecveis光敏剂

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"Lu00ecquido crystalline phases (lamellar cubic) as a release system for topical use of compounds fotossensu00ecveis (photosensitizers) of families of ftalocianinas,Porphyrins and clorinas used in photodynamic therapy (PDT) and fotodiagnu00f3stico (FD).The liquid crystalline phases, lamellar and cubic, referred to in this patent, are essentially formed by: 95 to 60% by weight, relative to the total weight of the composition.An unsaturated fatty acid called glyceryl glicerila (monoleu00edna), containing an acyl chain of 18 carbons, and 5 to 40% by weight of water.This composition is, in the limit of temperature between 20 and 75 198 C, the texture of a liquid crystalline gel, and preferably, the cubic phase.The photosensitive compounds (photosensitizers) incorporated in these stages are lamellar and cubic belonging to the families of the ftalocianinas, porphyrins and clorinas, in the proportion of 0.05 to 2% by weight, in relation to total composition, or any other composition which does not cause any change in the structure of these phases.
机译：Lecquido晶相（层状立方晶）作为释放系统用于光动力学疗法（PDT）和fotodiagn u003f3stico（FD）中的ftalocianinas，卟啉和clorinas家族的化合物fotossens u00ecveis（光敏剂）。相对于组合物的总重量，该专利中所指的层状和立方液晶相基本上由以下物质形成：相对于组合物的总重量，其为95至60重量％。一种不饱和脂肪酸，称为甘油基甘油（monole u00edna），其包含具有18个碳原子和5至40％重量的水的酰基链。在20至75 <198> C的温度范围内，该组合物为液晶凝胶的质地，最好为立方相。在这些阶段中掺入的光敏化合物（光敏剂）是片状和立方的，属于镰刀菌类，卟啉和克隆的家族，相对于总组合物或任何其他组合物的重量比为0.05％至2％这不会导致这些阶段的结构发生任何变化。

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