首页> 外国专利> Suspension, methods for preparing a suspension with fibrinogen and thrombin, coating a vehicle with a suspension, and drying a suspension of fibrinogen, thrombin and alcohol, collagen sponge coated with a fibrinogen and thrombin coating, and using a sponge of coated collagen

Suspension, methods for preparing a suspension with fibrinogen and thrombin, coating a vehicle with a suspension, and drying a suspension of fibrinogen, thrombin and alcohol, collagen sponge coated with a fibrinogen and thrombin coating, and using a sponge of coated collagen

机译：悬浮液，用纤维蛋白原和凝血酶制备悬浮液，用悬浮液涂覆媒介物并干燥悬浮液的方法，纤维蛋白原，凝血酶和酒精的悬浮液，涂覆有纤维蛋白原和凝血酶涂层的胶原蛋白海绵，以及使用涂覆的胶原蛋白的海绵

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"SUSPENSION, METHODS FOR PREPARING A FIBRINOGEN AND THROMBINE SUSPENSION, FOR COATING A VEHICLE WITH A SUSPENSION, AND FOR DRYING A FIBRINOGEN SUSPENSION, TROMBINE AND ALCOHOL, TRENBINE AND A TRENGINE REINENGE COLONING SPONG COLLAGEN SPONGE COATED ". A suspension of fibrinogen, thrombin, alcohol and optionally aprotinin is obtained by mixing and fibrinogen in alcohol with thrombin in alcohol. The suspension contains fibrinogen and thrombin particles with an average Folk Ward diameter of 25-100 Âµm. Thrombin may be human, bovine or recombinant. Fibrinogen may be human or recombinant. A method for coating a vehicle, such as a collagen sponge, with the suspension, and a method for drying the coating is exposed. The coated collagen carrier may be used as a ready-to-use absorbable composition for tissue bonding, tissue sealing and hemostasis, wherein the carrier is coated with solidly fixed components of fibrin glue, ie fibrinogen and thrombin.

机译：“悬浮液，制备纤维蛋白原和凝血酶悬浮液的方法，用悬浮液涂覆车辆，以及干燥纤维蛋白原悬浮液，肌醇和酒精，肌酐和丁宁的弹性增强海绵胶原蛋白海绵。纤维蛋白原，凝血酶，乙醇和抑肽酶的悬浮液是通过将乙醇中的纤维蛋白原与凝血酶在醇中混合而获得的。该悬浮液包含纤维蛋白原和凝血酶颗粒，平均民间病房直径为25-100 µm。凝血酶可以是人的，牛的或重组的。纤维蛋白原可以是人的或重组的。公开了用悬浮液涂覆媒介物例如胶原蛋白海绵的方法和干燥涂层的方法。涂覆的胶原蛋白载体可以用作用于组织粘合，组织密封和止血的即用型可吸收组合物，其中该载体涂覆有血纤蛋白胶的牢固固定成分，即血纤蛋白原和凝血酶。

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公开/公告号BR0206709A

专利类型
公开/公告日2004-02-17

原文格式PDF
申请/专利权人 NYCOMED PHARMA AS;
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申请/专利号BR20020206709
发明设计人 ALFRED SCHAUFLER;
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申请日2002-01-25
分类号A61L24/10;A61L15/32;
国家 BR
入库时间 2022-08-21 23:12:08

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