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Embedded radiation emitter for the localization and dosimetry of brachytherapy seed implants

机译：嵌入式辐射发射器，用于近距离放射治疗植入物的定位和剂量测定

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摘要

A device and method for improving the identification, localization, and dosimetry of brachytherapy seeds. The device is a brachytherapy seed comprising a therapeutic isotope and a marker isotope having an activity that is a fraction of the activity produced by the therapeutic isotope. The marker isotope emits positrons and/or photons capable of being imaged using radiation detection devices (e.g., positron emission tomography (PET), single-photon emission computed tomography (SPECT), gamma camera, computed tomography (CT)). The radiation dose of the marker isotope delivered beyond the immediate vicinity of the brachytherapy seed is low because the marker isotope is adapted to have an activity of at least one to two orders of magnitude lower than the activity of the therapeutic isotope. Thus, the presence of the marker isotope will not alter the therapeutic characteristics of the brachytherapy seed.

机译：一种用于改善近距离放射治疗种子的识别，定位和剂量测定的装置和方法。该装置是包括治疗同位素和标记同位素的近距离放射治疗种子，该标记同位素具有的活性是该治疗同位素产生的活性的一部分。标记同位素发射能够使用辐射检测装置成像的正电子和/或光子（例如，正电子发射断层扫描（PET），单光子发射计算机断层扫描（SPECT），伽马相机，计算机断层扫描（CT））。传递到近距离放射治疗种子的紧邻附近的标记同位素的辐射剂量低，因为标记同位素的活性比治疗同位素的活性低至少一到两个数量级。因此，标记同位素的存在不会改变近距离放射治疗种子的治疗特性。

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公开/公告号US2004006255A1

专利类型
公开/公告日2004-01-08

原文格式PDF
申请/专利权人 SAJO ERNO;WILLIAMS MARK L.;
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申请/专利号US20020188596
发明设计人 MARK L. WILLIAMS;ERNO SAJO;
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申请日2002-07-02
分类号A61N5/00;
国家 US
入库时间 2022-08-21 23:14:30

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