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Monitoring patient compliance and bioavailability of drugs by deproteinizing body fluids

机译:通过去除体液中的蛋白质来监测患者的依从性和药物的生物利用度

摘要

The present invention is a method for drug level detection by using a simplified and effective deproteinizing step from body fluids, such as plasma, blood, urine, saliva, tear fluid, followed by drug extraction and measurement using an accurate technique, such as a colorimetric assay or a High-Performance Liquid Chromatography method. In a particular embodiment, the invention is directed to a method to quantify rifampicin in order to monitor its levels in body fluids and also to a Kit for rifampicin concentration measurement.
机译:本发明是一种用于药物水平检测的方法,其通过使用从血浆,血液,尿液,唾液,泪液等体液的简化且有效的脱蛋白步骤,然后使用诸如比色法的精确技术提取和测量药物分析或高效液相色谱法。在一个特定的实施方案中,本发明涉及定量利福平以监测其在体液中的水平的方法,并且还涉及用于利福平浓度测量的试剂盒。

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