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Nucleotide sequence of escherichia coli pathogenicity islands

机译:大肠杆菌致病岛的核苷酸序列

摘要

The present invention relates to novel genes located in two chromosomal regions within uropathogenic E. coli that are associated with virulence. These chromosomal regions are known as pathogenicity islands (PAIs). In particular, the present application discloses 142 sequenced fragments (contigs) of DNA from two pools of cosmids covering pathogenicity islands PAI IV and PAI V located on the chromosome of the uropathogenic Escherichia coli J96. Further disclosed are 351 predicted protein-coding open reading frames within the sequenced fragments.
机译:本发明涉及位于泌尿致病性 E内两个染色体区域的新基因。大肠杆菌与毒力有关。这些染色体区域称为致病岛(PAI)。特别地,本申请公开了来自粘粒池的两个池的DNA的142个测序片段(重叠群),所述粘粒池覆盖位于尿路致病性大肠杆菌J96的染色体上的致病岛PAI IV和PAIV。进一步公开了测序的片段内的351个预测的蛋白质编码开放阅读框。

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