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Method of identifying chemical compounds having selected properties for a particular application

机译:识别具有针对特定应用的选定特性的化合物的方法

摘要

A method for obtaining compounds having selected properties for a particular application by forming base modules having at least two structural diversity elements from the reaction of a first compound having at least one structural diversity element and a first reactive group, with a second compound having at least one structural diversity element and a second reactive group, wherein the first and second groups combine by an addition reaction; producing a first array of molecules by varying at least one of the structural diversity elements of the compounds when producing the base modules; and screening the array to determine a first suitable compound for the particular application. The base modules are preferably formed form oxazolone- and aminimide-derived compounds. If desired, the method can be repeated by producing a second array of molecules through the formation of base modules having structural diversity elements that are modified from those of the first suitable compound; and screening the second array of molecules to determine a second suitable compound for the particular application. The second array producing and screening steps can be repeated as often as necessary to achieve an optimum compound for the particular application.
机译:一种通过具有至少一种结构多样性元素和第一反应基团的第一化合物与具有至少一个结构多样性元素的第二化合物的反应形成具有至少两个结构多样性元素的基础模块而获得具有特定性能的化合物的方法一个结构多样性元素和一个第二反应基团,其中第一和第二基团通过加成反应结合;当生产基础模块时,通过改变化合物的至少一种结构多样性元素来生产分子的第一阵列;筛选该阵列以确定用于特定应用的第一合适化合物。基本模块优选由恶唑酮和氨基酰亚胺衍生的化合物形成。如果需要的话,可以通过形成具有结构多样性元素的基本模块来形成第二分子阵列来重复该方法,所述基本模块具有从第一合适化合物的结构上改变的结构多样性元素。筛选第二分子阵列以确定用于特定应用的第二合适化合物。可以根据需要重复执行第二阵列的生产和筛选步骤,以实现针对特定应用的最佳化合物。

著录项

  • 公开/公告号US2004161610A1

    专利类型

  • 公开/公告日2004-08-19

    原文格式PDF

  • 申请/专利权人 HOGAN JOSEPH C.;

    申请/专利号US20040764112

  • 发明设计人 JOSEPH C. HOGAN;

    申请日2004-01-23

  • 分类号B32B9/04;

  • 国家 US

  • 入库时间 2022-08-21 23:22:29

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