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Compositions and methods for promoting paracellular penetration of epithelial and endothelial barriers
Compositions and methods for promoting paracellular penetration of epithelial and endothelial barriers
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机译：促进上皮和内皮屏障旁细胞渗透的组合物和方法
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摘要
Compositions and methods for enhancing paracellular permeability at an absorption site in a subject are disclosed. The method includes: (a) administering an effective amount of a phospholipase C inhibitor to a subject at a time in which enhanced paracellular permeability is desired; and (b) enhancing paracellular permeability in the subject at the absorption site through the administering of the effective amount of the phospholipase C inhibitor. The disclosed compositions and methods provide enhanced absorption of a hydrophilic drug in a subject.
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