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Solid support carrying functionalized dendrimer, useful for immobilization or synthesis of e.g. nucleic acids or proteins, particularly as biochip for studying interactions

机译：带有官能化树枝状聚合物的固体载体，可用于固定或合成例如核酸或蛋白质，特别是作为研究相互作用的生物芯片

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摘要

Solid support (A) has at least one surface covalently functionalized by a phosphorus-containing dendrimer (B) that comprises: (i) a central core, containing at least two functional groups; and (ii) at its periphery several functional groups that allow attachment, or in situ synthesis, of molecules of interest (C). (B) has size 1-20 nm. Independent claims are also included for: (1) preparing (A); (2) biochip or 'dendrichip' comprising (A) with (C) covalently attached to it; and (3) preparing the chips of (2).

机译：固体载体（A）具有至少一个被含磷的树枝状聚合物（B）共价官能化的表面，该表面包含：（i）含有至少两个官能团的中心核; （ii）在其外围具有几个官能团，这些官能团允许附着或原位合成目标分子（C）。（B）具有1-20 nm的大小。还包括以下方面的独立权利要求：（1）准备（A）; （2）生物芯片或“树状芯片”，其包含（A）与（C）共价连接的生物芯片或“ dendrichip”; （3）准备（2）的芯片。

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公开/公告号FR2838737A1

专利类型
公开/公告日2003-10-24

原文格式PDF
申请/专利权人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;
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申请/专利号FR20020005049
发明设计人 TREVISIOL EMMANUELLE;LECLAIRE JULIEN;PRATVIEL GENEVIEVE;CAMINADE ANNE MARIE;FRANCOIS JEAN;MAJORAL JEAN PIERRE;MEUNIER BERNARD;
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申请日2002-04-23
分类号C07B47/00;C12Q1/68;G01N33/543;G01N33/68;
国家 FR
入库时间 2022-08-21 23:37:42

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