FIELD: genetic engineering, molecular biology, biotechnology. SUBSTANCE: invention relates to technology of isolation of yeast proteins and nucleotide sequence of gene LEU2 of Yarrowia lipolityca, recombinant DNA-materials each of that comprises except for nucleotide sequence of gene LEU2 of Yarrowia lipolityca the human prorenin or anaphylatoxin gene and to strains of Yarrowia lipolityca transformed with recombinant DNA-material and able to produce human prorenin or anaphylatoxin. Invention provides safety preparing rather high amount of human proteins prorenin and anaphylatoxin in easily separable functional form. EFFECT: improved method of preparing, valuable properties. 19 cl, 8 tbl
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