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Active fraction having inhibitory effects on adipocytes NIH3T3-L1 cell isolated from medicinal plants

机译:活性成分对从药用植物分离的脂肪细胞NIH3T3-L1细胞具有抑制作用

摘要

PURPOSE: A composition containing an active fraction having inhibitory effect on adipocytes (NIH3T3-L1 cell) isolated from medicinal plants such as Agrimonia pilosa, Dianthus chinensis or the like is provided. The active fraction specifically shows inhibiting activity of obesity on a Lepr¬db/Lepr¬db mouse, as an animal model and is thus used as a therapeutic or preventing agent for obesity. CONSTITUTION: A composition contains an active fraction having inhibitory effect on adipocytes (NIH3T3-L1 cell) isolated from medicinal plants such as Agrimonia pilosa, Dianthus chinensis, Thuja orientalis and Pinelliae Rhizoma and additionally pharmaceutically acceptable carriers or excipients. One or more active fractions are obtained by extracting the herbal plants in a solvent such as purified water, C1-5 alcohols such as ethanol, methanol, propanol, butanol and ethanol or an organic solvent. The active component is administered in a range of 1 to 1,000mg/day per adult weight.
机译:用途:提供一种组合物,其包含对从药用植物如松香,石竹等中分离的脂肪细胞(NIH3T3-L1细胞)具有抑制作用的活性级分。所述活性级分作为动物模型特别显示出对Lepr-db / Lepr-db小鼠的肥胖的抑制活性,因此被用作肥胖的治疗剂或预防剂。组成:一种组合物含有一种活性成分,该成分对从药用植物(如非洲龙牙草,石竹,侧柏和半夏)分离的脂肪细胞(NIH3T3-L1细胞)具有抑制作用,此外还含有药学上可接受的载体或赋形剂。通过在溶剂如纯净水,C1-5醇如乙醇,甲醇,丙醇,丁醇和乙醇或有机溶剂中萃取草药植物,可获得一种或多种活性级分。活性成分的给药量为每成人体重1至1,000mg /天。

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