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REGULATION OF HUMAN EXTRACELLULAR CALCIUM-SENSING G PROTEIN-COUPLED RECEPTOR

机译：人体细胞钙敏感G蛋白偶联受体的调节

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摘要

Reagents which regulate human extracellular calcium sensing G protein-coupled receptor and reagents which bind to human extracellular calcium-sensing GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism, neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.

机译：调节人类细胞外钙敏感G蛋白偶联受体的试剂和与人类细胞外钙敏感GPCR基因产物结合的试剂可在预防，改善或纠正功能障碍或疾病（包括但不限于肥胖症和相关疾病）中发挥作用肥胖，癌症，糖尿病，骨质疏松症，焦虑症，抑郁症，高血压，偏头痛，强迫症，精神分裂症，自闭症，神经退行性疾病（例如阿尔茨海默氏病，帕金森病和亨廷顿舞蹈病），以及癌症化学疗法引起的呕吐。

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公开/公告号EP1335978A2

专利类型
公开/公告日2003-08-20

原文格式PDF
申请/专利权人 BAYER AKTIENGESELLSCHAFT;
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申请/专利号EP20010993685
发明设计人 XIAO YONGHONG;
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申请日2001-11-08
分类号C12N15/12;C07K14/705;G01N33/68;C12Q1/68;A61K38/17;A61K31/7088;
国家 EP
入库时间 2022-08-21 23:49:13

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