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MEDICINES FOR TRANSDERMAL ADMINISTRATION OF AN ESTROGEN OR PROGESTINE OR A MIXTURE THEREOF
MEDICINES FOR TRANSDERMAL ADMINISTRATION OF AN ESTROGEN OR PROGESTINE OR A MIXTURE THEREOF
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机译:经皮给予雌激素或孕激素或其混合物的药物
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摘要
Pharmaceutical formulation in the form of a gel suitable for the transdermal administration of an active agent of the class of estrogens or of progestin class or of a mixture of both, comprising: as permeation enhancers of the above said active agents a combination consisting substantially of an aliphatic alcohol having general formula CH3(CH2)nCH2OH wherein n = 8-16 and of a monoalkylether of diethylene glycol; as a vehicle or carrier, a combination of an alkanol of 2 DIVIDED 4 C atoms, a glycol and water; as gelling agent a polymer or copolymer of acrylic acid; a tertiary amine as a thickening and neutralizing agent.
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