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MEDICINES FOR TRANSDERMAL ADMINISTRATION OF AN ESTROGEN OR PROGESTINE OR A MIXTURE THEREOF

机译:经皮给予雌激素或孕激素或其混合物的药物

摘要

Pharmaceutical formulation in the form of a gel suitable for the transdermal administration of an active agent of the class of estrogens or of progestin class or of a mixture of both, comprising: as permeation enhancers of the above said active agents a combination consisting substantially of an aliphatic alcohol having general formula CH3(CH2)nCH2OH wherein n = 8-16 and of a monoalkylether of diethylene glycol; as a vehicle or carrier, a combination of an alkanol of 2 DIVIDED 4 C atoms, a glycol and water; as gelling agent a polymer or copolymer of acrylic acid; a tertiary amine as a thickening and neutralizing agent.
机译:适于透皮给药雌激素类或孕激素类活性剂或两者的混合物的凝胶形式的药物制剂,其包含:作为上述活性剂的渗透促进剂,基本上由药物组合物组成的组合通式为CH 3(CH 2)n CH 2 OH的脂肪族醇,其中n = 8-16,是二甘醇的单烷基醚。作为载体或载体,是2个分开的4 C原子的链烷醇,乙二醇和水的组合;作为胶凝剂的是丙烯酸的聚合物或共聚物;叔胺作为增稠和中和剂。

著录项

  • 公开/公告号AT238801T

    专利类型

  • 公开/公告日2003-05-15

    原文格式PDF

  • 申请/专利权人 PERMATEC N.V.;

    申请/专利号AT19970108989T

  • 发明设计人 CARRARA DARIO;

    申请日1997-06-04

  • 分类号A61K31/565;A61K9/06;A61K9/70;A61K47/10;A61K47/18;A61K47/32;

  • 国家 AT

  • 入库时间 2022-08-21 23:59:54

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