首页> 外国专利> PHARMACEUTICAL COMPOSITIONS COMPRISING 2-AMINO-1,3-PROPANEDIOL DERIVATIVES FOR PREVENTING AND/OR TREATING CHRONIC REJECTION IN A RECIPIENT FOR ORGAN OR TISSUE ALLO- OR XENOTRANSPLANTS

PHARMACEUTICAL COMPOSITIONS COMPRISING 2-AMINO-1,3-PROPANEDIOL DERIVATIVES FOR PREVENTING AND/OR TREATING CHRONIC REJECTION IN A RECIPIENT FOR ORGAN OR TISSUE ALLO- OR XENOTRANSPLANTS

机译:包含2-氨基-1,3-丙二酮衍生物的药物组合物,用于预防和/或治疗异种或异种异种或器官异种植物的慢性排斥反应

摘要

A pharmaceutical composition for preventing or treating graft vessel diseases in a recipient of organ or tissue allo- or xenotransplant or for preventing or controlling acute rejection in a xenograft transplant recipient, comprising a compound of the formula wherein R1 is an optionally substituted straight- or branched carbon chain having 12 to 22 carbon atoms which may be optionally interrupted by an optionally substituted phenylene, and each of R3, R5, R4 and R5, independently, is H or lower alkyl, in free form or in a pharmaceutically acceptable salt form, together with one or more pharmaceutically acceptable diluents or carriers therefor.
机译:用于预防或治疗同种异体或异种器官或组织的受体中的移植血管疾病或用于预防或控制异种移植受体的急性排斥的药物组合物,其包含下式的化合物,其中R 1是任选取代的直链或支链具有12至22个碳原子的碳链,其可任选地被任选取代的亚苯基中断,并且R 3,R 5,R 4和R 5各自独立地为H或低级烷基,呈游离形式或药学上可接受的盐形式与一种或多种药学上可接受的稀释剂或载体。

著录项

  • 公开/公告号IL129824B

    专利类型

  • 公开/公告日2003-07-31

    原文格式PDF

  • 申请/专利权人 NOVARTIS AG;

    申请/专利号IL129824

  • 发明设计人

    申请日1999-05-06

  • 分类号

  • 国家 IL

  • 入库时间 2022-08-22 00:02:42

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