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Antigens associated with polymyositis and with dermatomyositis

机译:与多发性肌炎和皮肌炎有关的抗原

摘要

Isolated DNA molecules encoding at least one epitope of the Mi-2 antigen and at least one epitope of the PM-Scl antigen are provided. The DNA may be used as probes to obtain related DNA. Proteins expressed from the DNA may be used in assays for the diagnosis of dermatomyositis and polymyositis, particularly polymyositis-scleroderma overlap disorders. The expressed proteins may also be used for purification of the associated autoantigens.
机译:提供了分离的DNA分子,其编码Mi-1抗原的至少一个表位和PM-Scl抗原的至少一个表位。该DNA可以用作获得相关DNA的探针。由DNA表达的蛋白质可以用于诊断皮肌炎和多发性肌炎,特别是多发性肌炎-硬皮病重叠疾病。表达的蛋白质也可用于纯化相关的自身抗原。

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