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Multi-imaging modality tissue mimicking materials for imaging phantoms

机译:用于成像体模的多成像模态组织模拟材料

摘要

Tissue-mimicking material suitable for phantoms for use with at least ultrasound and MRI have sections of material in contact with each other which mimic ultrasound and magnetic resonance imaging properties of human tissues, and preferably also computed tomography properties, so that the phantom can be used for the testing of imaging by various types of medical imagers. A suitable tissue-mimicking material for use in phantoms of this type includes an aqueous mixture of large organic water soluble molecules, a copper salt, a chelating agent for binding the copper ions in the salt, and a gel-forming material. Small glass beads may be intermixed therewith to provide a selected ultrasound attenuation coefficient without substantially affecting the MRI properties of the material. Larger glass beads may be used in a section to control primarily the ultrasound backscatter coefficient without significant effect on the ultrasound attenuation coefficient. Tissue-mimicking material that simulates muscle may have smaller glass beads and a higher concentration of gel-forming material than an adjacent section. Such similar materials in contact with one another show relative stability over extended periods of time.
机译:适用于至少与超声波和MRI配合使用的人体模型的组织模仿材料具有彼此接触的材料部分,这些部分模仿人体组织的超声波和磁共振成像特性,并且最好还具有计算机断层扫描特性,因此可以使用人体模型。用于各种类型的医学成像仪的成像测试。适用于这种体模的组织模拟材料包括大型有机水溶性分子,铜盐,用于结合盐中铜离子的螯合剂和凝胶形成材料的水性混合物。小玻璃珠可与其混合以提供选定的超声衰减系数,而基本上不影响材料的MRI特性。较大的玻璃珠可用于某个部分,以主要控制超声的反向散射系数,而对超声衰减系数没有明显影响。模拟肌肉的组织模拟材料与相邻部分相比,可能具有更小的玻璃珠和更高浓度的凝胶形成材料。彼此接触的此类相似材料在延长的时间段内显示出相对稳定性。

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