;and stereoisomers KF-1040T5A and KF-1040T5B which are compounds represented by the following formula [II], ;is cultivated in a culture medium to accumulate KF-1040T4A and/or KF-1040T4B and/or KF-1040T5A and/or KF-1040T5B in the culture medium, and the substance KF-1040T4A and/or KF-1040T4B and/or KF-1040T5A and/or KF-1040T5B are harvested from the culture medium. The obtained substances are useful for the prevention and treatment of the diseases relating to arteriosclerosis, obesity, thrombosis, inflammations and immunofunctional disorders."/>
Substances KF-1040T4A,KF-1040T4B, KF-1040T5A, and KF-1040T5B, and process for producing same
A microorganism which belongs to the genus Gliocladium and has the ability to produce stereoisomers KF-1040T4A and KF-1040T4B which are compounds represented by the following formula [I], ;and stereoisomers KF-1040T5A and KF-1040T5B which are compounds represented by the following formula [II], ;is cultivated in a culture medium to accumulate KF-1040T4A and/or KF-1040T4B and/or KF-1040T5A and/or KF-1040T5B in the culture medium, and the substance KF-1040T4A and/or KF-1040T4B and/or KF-1040T5A and/or KF-1040T5B are harvested from the culture medium. The obtained substances are useful for the prevention and treatment of the diseases relating to arteriosclerosis, obesity, thrombosis, inflammations and immunofunctional disorders.
展开▼
机译：一种微生物，它属于胶质金毛囊藻属，具有产生立体异构体KF-1040T4A和KF-1040T4B的能力，这些异构体由下式＆lsqb; I＆rsqb;表示， =“嵌入式图片”文件=“ US06608185-20030819-C00001.GIF” he =“ 79.2099” id =“ EMI-C00001” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 214.58115” /> ;和立体异构体KF-1040T5A和KF-1040T5B，它们由下式＆lsqb; II＆rsqb;表示， ;是一种文化培养基中积聚KF-1040T4A和/或KF-1040T4B和/或KF-1040T5A和/或KF-1040T5B在物质中以及物质KF-1040T4A和/或KF-1040T4B和/或KF-1040T5A和/或从培养基中收获KF-1040T5B。所获得的物质可用于预防和治疗与动脉硬化，肥胖，血栓形成，炎症和免疫功能障碍有关的疾病。
展开▼
